Browsing by Author "Maja, Lineo"

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    Comorbidity and haemodialysis adequacy in end-stage kidney disease patients in Lesotho
    (International Health Review, 2024-12-19) Polile, Rasemoko, P; Lehloenya, Boitumelo; Maja, Lineo; Raute, Molise
    Background: Low- and middle-income countries including Lesotho are faced with a huge burden of end-stage kidney disease in people experiencing human immune virus (HIV), hypertension (HTN) and diabetes mellitus (DM). Objectives: To assess the comorbidity, mortality rate and evaluate the haemodialysis adequacy in patients with end-stage kidney disease in Motebang government hospital. Methods: A retrospective study was conducted in 142 adult male and female patients enrolled for haemodialysis from 1st October 2017 to 30th June 2023 in Motebang government hospital. Patient’s characteristics and clinical outcomes data were analysed using descriptive statistics Results: Among 142 patients enrolled, there were 84 (59.2%) males and 58 (40.8%) females. 19 (13.4%) patients were below 34 years while 33 (23.3%) patients were between 45 and 64 years. In all age groups, 41 (28.9%) patients had HIV, 37 (26.1%) patients had HTN alone and 24 (16.9%) patients had combination of HTN and DM. In 63 deceased patients, there were 36 (57.1%) males and 27 (42.7%) females. Among deceased, 18 (28.5%) patients had HIV, 15 (23.8%) had combination of HTN and DM, 14 (22.3%) patients had HTN alone, while all the patients (99.3%) were also anaemic. Since 2017, 19 (30.2%) patients died in 2020, 12 (19%) died in 2022 while only 4 (6.3%) patients died up to date (June 2023). Among 79 patients, only 1 (1.3%) patient had urea- reduction ratio (URR) greater than 65%. Conclusions: Chronic diseases are the major risks factors in patients with end-stage kidney disease in Motebang hospital. Haemodialysis adequacyshould form the integral part of monitoring in patients with end-stage kidney disease to prolong life
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    Knowledge Attitudes and Practice about HIV Transmission, Prevention and Treatment among Elderly Patients with HIV/AIDS in Rural Lesotho
    (Journal of Pharmaceutical Care & Health Systems, 2021-05-06) Ramathebane, Maseabata; Maja, Lineo; Molungoa, Sello; Sayed, Abdul Rauf
    Introduction: Lesotho is one of the world’s countries hardest hit by HIV, with the second highest HIV prevalence after Swaziland. Elderly persons face many prevention challenges such as lack of knowledge in HIV/AIDS, discrimination and stigmatization that can lead to late testing, diagnosis and reluctance in seeking medical services. This is the first study conducted in Lesotho to assess knowledge regarding HIV transmission, prevention and treatment among elderly patients in rural Lesotho. Methods: The study population composed of elderly HIV/AIDS patients aged ≥ 50 years, receiving clinical services within the catchment of four rural clinics of Maseru districts. A random sample of medical records of patients living with HIV/AIDS was selected from each of the four clinics. After intervention interview were carried out using the same tool that was used at baseline. Results: Before intervention, a total of 269 patients were interviewed. Majority of the patients were females (65.8%) and had achieved only a primary level of education (71.4%). A composite score was derived from all the questions relating to knowledge about HIV transmission and treatment. A patient who achieved a composite score ≥ 75% was defined as having ‘adequate knowledge’. The results showed that only 34.2% of the patients had adequate knowledge of transmission and treatment of HIV/AIDS. Adequate knowledge about HIV transmission, prevention and treatment was significantly associated with gender, females being more knowledgeable than males (OR=1.9, 95% CI: 1.1-3.5; P=0.022). Patients with secondary or higher level of education being more knowledgeable than those with less education (OR=2.8, 95% CI: 1.1-7.8; P=0.021). After controlling for age, gender and educational level, the results from multivariate logistic regression analysis showed similar associations to the unadjusted ORs. Over one-third of the patients (36.8%) had unprotected sex. After intervention, a total of 183 patients were interviewed. Patients with no formal education gained more knowledge (OR=6.5 95% CI: 1.5-59.3; P=0.005). Males also gained more knowledge after intervention (OR=4.4, 95% CI: 1.6-14.9; P=0.001). Age group of + 65 also gained more knowledge (OR=6.5 95% CI: 1.5-59.3; P=0.005). Conclusion: There is a lack of knowledge about transmission and prevention among elderly patients living with HIV/AIDS in rural Lesotho. It is imperative that a targeted strategy be developed for this vulnerable group, taking into cognisance their inherent lower level of education and to improve access to services. After intervention there was a significant amount of knowledge gained particularly by the groups of patients that had less knowledge about HIV transmission and prevention